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Henriette Farkas Selected Research

Plasma Kallikrein

12/2023Once-Daily Oral Berotralstat for Long-Term Prophylaxis of Hereditary Angioedema: The Open-Label Extension of the APeX-2 Randomized Trial.
11/2023An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: a two-part, randomised, double-blind, placebo-controlled, crossover phase 2 trial.
6/2021Long-term safety and effectiveness of berotralstat for hereditary angioedema: The open-label APeX-S study.
1/2021Angioedema Without Wheals: Challenges in Laboratorial Diagnosis.
1/2021Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial.
2/2019Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies.
1/2018Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

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Henriette Farkas Research Topics

Disease

100Hereditary Angioedemas
04/2024 - 12/2003
37Angioedema
02/2024 - 09/2004
14Edema (Dropsy)
04/2024 - 12/2003
8Rare Diseases (Rare Disease)
11/2023 - 01/2011
6Acquired angioedema
01/2023 - 05/2006
3Infections
11/2023 - 07/2010
3Hypersensitivity (Allergy)
11/2023 - 01/2019
3Autoimmune Diseases (Autoimmune Disease)
01/2020 - 10/2011
3Atherosclerosis
01/2019 - 04/2005
3Neoplasms (Cancer)
03/2011 - 01/2008
2Venous Thrombosis (Deep-Vein Thrombosis)
11/2023 - 05/2006
2Abdominal Pain (Pain, Abdominal)
04/2023 - 01/2021
2Inflammation (Inflammations)
04/2022 - 02/2012
2Anaphylaxis (Anaphylactic Shock)
02/2014 - 01/2011
2Seasonal Allergic Rhinitis (Hay Fever)
05/2003 - 08/2002
1Inborn Genetic Diseases (Disease, Hereditary)
02/2024
1COVID-19
11/2023
1Urticaria (Hives)
01/2023
1Insulin Resistance
04/2022
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
04/2022
1Helicobacter Infections
04/2022
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
01/2022
1Erythema
06/2021
1Vomiting
01/2021
1Diarrhea
01/2021
1Back Pain (Backache)
01/2021
1Thromboembolism
03/2016
1Polycythemia (Erythrocytosis)
02/2016
1Cardiac Arrhythmias (Arrythmia)
01/2015

Drug/Important Bio-Agent (IBA)

25BradykininIBA
11/2023 - 12/2011
18Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA
11/2023 - 12/2003
14Complement System Proteins (Complement)IBA
11/2023 - 06/2003
10Danazol (Azol)FDA LinkGeneric
01/2019 - 04/2005
9icatibantIBA
01/2021 - 08/2010
8AntibodiesIBA
01/2023 - 01/2011
7Plasma KallikreinIBA
12/2023 - 01/2018
7Proteins (Proteins, Gene)FDA Link
11/2022 - 12/2003
6Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
04/2024 - 01/2008
6Biomarkers (Surrogate Marker)IBA
01/2023 - 04/2016
6AndrogensIBA
01/2022 - 07/2010
5Kallikreins (Kallikrein)IBA
02/2024 - 01/2018
5berotralstatIBA
12/2023 - 01/2018
5AutoantibodiesIBA
01/2023 - 02/2007
4Histamine Antagonists (Antihistamines)IBA
04/2023 - 05/2003
4Factor XII (Hageman Factor)IBA
11/2021 - 07/2010
4conestat alfaIBA
03/2020 - 11/2008
3C-Reactive ProteinIBA
01/2019 - 06/2003
3Tranexamic Acid (AMCA)FDA Link
03/2016 - 08/2010
2KininsIBA
02/2024 - 02/2019
2sebetralstatIBA
11/2023 - 09/2023
2GlucocorticoidsIBA
04/2023 - 01/2014
2alpha-2-HS-GlycoproteinIBA
04/2022 - 01/2019
2Bradykinin B2 ReceptorIBA
01/2020 - 06/2016
2Peptides (Polypeptides)IBA
01/2020 - 01/2019
2Serine Proteases (Serine Protease)IBA
01/2020 - 10/2015
2Neutralizing AntibodiesIBA
01/2019 - 02/2014
2LipidsIBA
01/2019 - 04/2005
2Endothelin-1 (Endothelin 1)IBA
02/2016 - 02/2012
2LectinsIBA
10/2015 - 12/2014
2EnzymesIBA
10/2015 - 12/2014
2Hormones (Hormone)IBA
01/2014 - 09/2004
2Immunoglobulin G (IgG)IBA
01/2012 - 03/2011
2Immunoglobulin M (IgM)IBA
10/2011 - 01/2011
2Adrenal Cortex Hormones (Corticosteroids)IBA
09/2007 - 08/2002
1Protease Inhibitors (Protease Inhibitor)IBA
04/2024
1inter-alpha-inhibitorIBA
04/2024
1Trypsin InhibitorsIBA
04/2024
1VaccinesIBA
11/2023
1ThrombinFDA Link
11/2023
1SDMIBA
09/2023
1Factor XIIa (Coagulation Factor XIIa)IBA
01/2023
1Monoclonal AntibodiesIBA
01/2023
1A-factor (Streptomyces)IBA
01/2023
1PlasminogenIBA
11/2021
1Angiopoietin-1IBA
11/2021
1Glucosamine (Dona)IBA
11/2021
1Heparitin Sulfate (Heparan Sulfate)IBA
11/2021
1Complement C1 (Complement 1)IBA
08/2021
1Interleukin-8 (Interleukin 8)IBA
06/2021
1High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA
01/2021
1Platelet Activating FactorIBA
01/2020
1Cholecalciferol (Vitamin D3)FDA Link
06/2019
1lanadelumabIBA
02/2019
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019
1acivicin (AT 125)IBA
01/2018
1Secretory Phospholipases A2IBA
01/2018
1Investigational DrugsIBA
01/2018
1Kininogens (Kininogen)IBA
12/2017
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
10/2017
1Atrial Natriuretic Factor (ANF)IBA
04/2016
1Testosterone (Sustanon)FDA Link
02/2016
1AdrenomedullinIBA
02/2016
1Arginine Vasopressin (Argipressin)IBA
02/2016
1Thyroid HormonesIBA
01/2016
1Leukocyte Elastase (Neutrophil Elastase)IBA
12/2015

Therapy/Procedure

31Therapeutics
11/2023 - 08/2002
2Aftercare (After-Treatment)
02/2016 - 12/2012
1Polypharmacy
01/2020
1Biological Therapy
01/2020
1Oral Administration
01/2018